Adalimumab (Humira) (Human)

Product Details:

Storage Store at 2C to 8C (refrigerated), do not freeze
Usage Treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohns disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, juvenile idiopathic arthritis
HS Code 30029099
Taste Odorless
Shelf Life 24 months
Molecular Formula C6428H9912N1694O1987S46
Appearance Clear to slightly opalescent solution
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Adalimumab (Humira) (Human) Product Specifications

Usage Treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohns disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, juvenile idiopathic arthritis
Storage Store at 2C to 8C (refrigerated), do not freeze
Purity(%) >99%
Chemical Name Adalimumab
Shelf Life 24 months
HS Code 30029099
Taste Odorless
Molecular Formula C6428H9912N1694O1987S46
Color Colorless to pale yellow
Appearance Clear to slightly opalescent solution
Physical Form Solution
Type Injection
Structural Formula Human monoclonal antibody IgG1 (schematic only)
Melting Point Not applicable (protein solution)
Smell Odorless
Other Names Humira
CAS No 331731-18-1
Poisonous No
Classification Monoclonal Antibody
Application Pharmaceutical
Shape Liquid
Grade Medical
Molecular Weight 148 kDa
Ph Level 4.8
Density 1.01 Gram per cubic centimeter(g/cm3)

Product Description

Adalimumab (Humira) is a recombinant human IgG1 monoclonal antibody specific for Tumor Necrosis Factor-Alpha (TNF-) and is used to treat rheumatic arthritis, intestinal disorders, dermatological diseases and cancer. Adalimumab specifically binds to TNF alpha and blocks its interaction with p55 and p75 cell surface TNF receptors and reduces the inflammation and subsequently improves the patients health. Drug level quantification can be important to adapt patient prescription or to switch to an alternative TNF inhibitor drug. EMA Bio-analytical Method Validation Guidelines and industry-recommended practices for ligand-binding assays were used for validation of this kit. This Adalimumab ELISA kit has been developed for specific quantification of Adalimumab concentration in human serum or plasma with high sensitivity and reproducibility. BioVisions Adalimumab ELISA kit is a sandwich ELISA assay for the quantitative measurement of Adalimumab in human serum, plasma. The density of color is proportional to the amount of human Adalimumab captured from the samples.

Size	100 assays
SKU+Size	K4253-100
Detection Method	Absorbance (450 nm)
Species Reactivity	Human
Applications	Quantitative measurement of Adalimumab in human serum and plasma
Features & Benefits	Easy, convenient, sensitive and time-saving method to measure the level of Adalimumab in human serum and plasma. Detection Range: 4.7 - 300 ng/ml
Kit Components	Micro ELISA Plate Adalimumab Standard (50 mg/ml) Detection Antibody (2000X) Assay Diluent TMB substrate (20X) (Avoid light) Wash bufferA (20X) Plate sealers
Storage Conditions	-20C
Shipping Conditions	Gel Pack
USAGE	For Research Use Only! Not For Use in Humans.

How Humira Works to Relieve Autoimmune Conditions

Humira targets and neutralizes the activity of tumor necrosis factor-alpha (TNF-alpha), a pro-inflammatory cytokine involved in autoimmune disorders. By inhibiting TNF-alpha, it helps reduce inflammation and alleviate symptoms associated with conditions like rheumatoid arthritis, psoriasis, and Crohns disease. Its use can improve patients quality of life by managing flare-ups and slowing disease progression.

Usage and Administration of Humira Prefilled Injectors

Humira is administered via subcutaneous injection, typically every two weeks, although frequency can vary according to the indication and patient response. It is available in convenient, single-use prefilled syringes or pens, allowing for self-administration at home following proper training. The solution is odorless and should appear clear to slightly opalescent when viewed before injection.

Safe Storage and Handling Requirements

To maintain stability and efficacy, Humira must be stored in a refrigerator at 2C to 8C and must not be frozen. Cold chain transport is recommended to ensure product integrity, and it maintains stability for up to 24 months under correct storage conditions. Expiration dates are clearly printed on the packaging.

FAQs of Adalimumab (Humira) (Human):

Q: How should I store Humira prefilled injectors?

A: Humira should be kept refrigerated at 2C to 8C. Avoid freezing the product and store it in its original packaging to protect it from light. Proper cold chain transport is advised.

Q: What conditions can Humira be used to treat?

A: Humira is prescribed for autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohns disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, and juvenile idiopathic arthritis.

Q: When and how often should Humira be administered?

A: The injection is usually administered every two weeks, but the frequency may vary based on the diagnosed condition and your doctors recommendation. Always follow your healthcare providers instructions.

Q: Where should Humira injections be administered on the body?

A: Humira is usually injected subcutaneously in the thigh or abdomen. Its important to rotate injection sites to minimize skin irritation. Your healthcare provider will give guidance on proper technique.

Q: What is the process for disposing of used Humira syringes or pens?

A: Used injectors must be disposed of safely as per hospital biohazard protocols or local regulations for medical sharps. Do not throw them in household trash.

Q: What are the main benefits of using Humira?

A: Humira can help reduce inflammation, relieve painful symptoms, prevent joint and tissue damage, and improve daily function for individuals with autoimmune diseases.

Q: Are there any contraindications for using Humira?

A: Humira should not be used in patients with known hypersensitivity to adalimumab or any of its excipients. Always disclose your medical history to your doctor before starting therapy.

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