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            Home » Products » Speciality Chemicals & Inhibitor » Borrelidin

            Borrelidin

            Borrelidin
            Borrelidin
            Product Code : 2367
            Brand Name : BioVision
            Product Description

             


             

            Borrelidin

            An angiogenesis inhibitor

            A macrolide antibiotic isolated from Streptomyces sp. An antiangiogenic (IC₅₀ = 0.8 nM) agent. Bacterial and eukaryal threonyl-tRNA synthetase (THrRS) inhibitor. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Also acts as a CDK inhibitor 

             



              FOR BULK REQUIREMENT - WE CAN PROVIDE SPECIAL PRICE USP, BP GRADE (PHARMA GRADE)


             

            SKU: 2367

            Availability: In stock


            SKU-Size



            2367-250250 µg
            15,950

            2367-10001 mg 46,750

             




             

            Alternate NameTreponemycin; U 78548; C2989
            Peptide SequenceWhite to off-white solid
            Formulation7184-60-3
            CAS #C₂₈H₄₃NO₆
            Molecular Formula489.64
            Molecular Weight≥98% by HPLC
            PurityDMSO (~10 mg/ml)
            SolubilityProtect from light and moisture
            SMILESCC1CC(CC(C(C(=CC=CCC(OC(=O)CC(C(C1)C)O)C2CCCC2C(=O)O)C#N)O)C)C
            InChiInChI=1S/C28H43NO6/c1-17-12-18(2)14-20(4)27(32)21(16-29)8-5-6-11-25(22-9-7-10-23(22)28(33)34)35-26(31)15-24(30)19(3)13-17/h5-6,8,17-20,22-25,27,30,32H,7,9-15H2,1-4H3,(H,33,34)/b6-5+,21-8-/t17-,18+,19-,20-,22+,23+,24-,25-,27+/m0/s1
            InChi KeyOJCKRNPLOZHAOU-UGKRXNSESA-N
            PubChem CID6436801
            MDL NumberMFCD01740784
            Storage Conditions-20 ̊C
            Shipping ConditionsGel Pack
            USAGE

            For Research Use Only! Not For Use in Humans.

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