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                          Home » Products » Speciality Chemicals & Inhibitor » Oligomycin D(CAS 1404-59-7)

                          Oligomycin D(CAS 1404-59-7)

                          Oligomycin D(CAS 1404-59-7)
                          Oligomycin D(CAS 1404-59-7)
                          Product Code : 1404-59-7
                          Product Description
                          DESCRIPTION
                          Synonyms

                          •     26-Demethyloligomycin A
                          •     RR 32705
                          •     Rutamycin

                          Oligomycin D is a macrolide antibiotic produced by several species of Streptomyces that inhibits the mitochondrial F1FO-ATPase and is used to uncouple oxidative phosphorylation from electron transport.1 Oligomycin D is reported to inhibit K-Ras plasma membrane localization in MDCK cells with an IC50 value of 3.49 nM and is cytotoxic to SW620 colon cancer cells with an IC50 value of 36 µM.2
                          TECHNICAL INFORMATION
                          Formal Name    (1S,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,29R)-22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,29-octamethyl-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione
                          CAS Number    1404-59-7

                          Synonyms    

                          •     26-Demethyloligomycin A
                          •     RR 32705
                          •     Rutamycin


                          Molecular Formula    C44H72O11
                          Formula Weight    777.0
                          Purity    ≥95%
                          Formulation    A lyophilisate
                          SMILES    C[C@H](C[C@H]1[C@@H](C)CC[C@@]2(C[C@@H]([C@@]([H])([C@@H](O2)CC[C@@]([H])(CC)/C=C/C=C/C[C@@H](C)[C@H](O)[C@@](O)(C3=O)C)C)OC(/C=C/[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)[C@@H](O)[C@@H]3C)=O)=O)O1)O
                          InChI Code    1S/C44H72O11/c1-11-33-16-14-12-13-15-27(4)41(50)43(10,52)42(51)32(9)40(49)31(8)39(48)30(7)38(47)26(3)17-20-37(46)53-36-24-44(54-34(19-18-33)29(36)6)22-21-25(2)35(55-44)23-28(5)45/h12-14,16-17,20,25-36,38,40-41,45,47,49-50,52H,11,15,18-19,21-24H
                          InChI Key    LVWVMRBMGDJZLM-BONFEJLISA-N

                          WARNING - This product is not for human or veterinary use.
                          SHIPPING & STORAGE
                          Storage    -20°C
                          Shipping    Wet ice in continental US; may vary elsewhere
                          Stability    As supplied, 2 years from the QC date provided on the Certificate of Analysis

                           


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