DESCRIPTION
Synonyms
LSF, a chiral metabolite of pentoxifylline, acts as a potent anti-inflammatory agent.1,2 (S)-LSF is the pharmacologically inactive optical enantiomer of (R)-LSF, the biologically active isomer.2 When metabolized by isolated human liver cells, pentoxifylline is exclusively reduced to (S)-LSF in the cytosol, while reduction in liver microsomes is 85% stereoselective in favor of (S)-LSF formation.3 Thus, pentoxifylline is an inefficient prodrug for the delivery of therapeutically relevant lisofylline.
TECHNICAL INFORMATION
Formal Name
3,7-dihydro-1-[5S-hydroxyhexyl]-3,7-dimethyl-1H-purine-2,6-dione
CAS Number
100324-80-9
Synonyms
Molecular Formula:C13H20N4O3
Formula Weight:280.3
Purity:98%
Formulation
A crystalline solid
SHIPPING & STORAGE
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
SR GROUP
All Rights Reserved.(Terms of Use) Developed and Managed by Infocom Network Private Limited. |