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ACS 67 Chemical

ACS 67 Chemical

6300-110300 INR

Product Details:

  • Shelf Life 24 Months
  • Melting Point REFER C.O.A MSDS
  • Smell Stimulus
  • Molecular Weight 598.8 Kilograms (kg)
  • Boiling point REFER C.O.A MSDS
  • Molecular Formula C32H38O5S3
  • Usage R&D FORMULATION
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ACS 67 Chemical Price And Quantity

  • 1 Pack
  • 6300-110300 INR

ACS 67 Chemical Product Specifications

  • POWDER
  • REFER C.O.A MSDS
  • C32H38O5S3
  • Bitter
  • Solid
  • C32H38O5S3
  • 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl ester, 5Z-heptenoic acid
  • R&D FORMULATION
  • 1088434-86-9
  • Crystal
  • 95%
  • TETRA HYDROXI STEAROL
  • 24 Months
  • 3821
  • WHITE
  • 598.8 Kilograms (kg)
  • High Purity
  • Stimulus
  • REFER C.O.A MSDS
  • Other
  • REFER C.O.A MSDS

ACS 67 Chemical Trade Information

  • Days after Acceptance (DA) Cheque Cash Advance (CA)
  • 10 Pack Per Day
  • 10-15 Days
  • Yes
  • Within a certain price range free samples are available
  • 1MG 5MG 10MG 25MG
  • Asia
  • All India

Product Description

DESCRIPTION

Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug for the treatment of glaucoma.1Latanoprost is an isopropyl ester, a prodrug form which is converted to latanoprost (free acid) by endogenous esterase enzymes. The free acid form is 200 times more potent than latanoprost as an FP receptor ligand for the human recombinant FP receptor.2 ACS 67 is an analog of latanoprost (free acid) that contains a hydrogen sulfide releasing component conjugated to the latanoprost carboxyl group.3 In glaucomatous pigmented rabbits, ACS 67 reduced intra-ocular pressure (IOP) more rapidly and to a greater extent than latanoprost (15 versus 25.5 mm Hg at four hours) at a dose of 0.005% for each compound.3 ACS 67 also increased the levels of reduced glutathione and cGMP in the aqueous humor of glaucomatous pigmented rabbits better than latanoprost.3

TECHNICAL INFORMATION

Formal Name

7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl ester, 5Z-heptenoic acid

CAS Number:1088434-86-9

Molecular Formula:C32H38O5S3

Formula Weight:598.8

Purity:95%

Formulation

A crystalline solid

 

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