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AFP 07 (free acid)

AFP 07 (free acid)
AFP 07 (free acid)
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Product Code : SRGCC76
Brand Name : S.R GROUP CHEMICALS
Price And Quantity
  • Minimum Order Quantity
  • 1
  • Unit of Measure
  • Pack/Packs
  • Price Range
  • 9800.00 - 78400.00 INR
  • Price
  • 9800-78400 INR
Product Specifications
  • Molecular Formula
  • C22H30F2O5
  • Melting Point
  • REFER C.O.A MSDS
  • Molecular Weight
  • 412.5 Kilograms (kg)
  • Appearance
  • POWDER
  • Density
  • REFER C.O.A MSDS
  • Shelf Life
  • 12 Months
  • Shape
  • Crystal
  • Boiling point
  • REFER C.O.A MSDS
  • Structural Formula
  • C22H30F2O5
  • Other Names
  • 5Z-[(3aR,4R,5R,6aS)-3,3-difluorohexahydro-5-hydroxy-4-[(1E,3S,4S)-3-hydroxy-4-methyl-1-nonen-6-ynyl]-2H-cyclopenta[b]furan-2-ylidene]-pentanoic acid
  • Usage
  • R&D FORMULATION
  • HS Code
  • 3821
  • Ph Level
  • REFER C.O.A MSDS
  • Taste
  • Bitter
  • Physical Form
  • Solid
  • Smell
  • Stimulus
  • Classification
  • High Purity
  • Chemical Name
  • Other
  • CAS No
  • 788799-13-3
  • Type
  • TETRA HYDROXI STEAROL
  • Purity(%)
  • 98%
  • Color
  • WHITE
Product Description

DESCRIPTION

Prostaglandin I2 is an unstable prostanoid which, through the ‘I prostanoid’ (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds. AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor (Ki = 0.561 nM).1 AFP 07 shows weaker affinity for EP receptors, with Ki values of > 100 nM for EP1-3 and > 10 nM for EP4.1 In piglet and rabbit saphenous veins, which express both IP and EP4, the EP4 antagonist AH 23848 reduces AFP 07-mediated relaxation, suggesting that AFP 07 activates EP4 as well as IP, particularly when both receptors are present.2

TECHNICAL INFORMATION

Formal Name

5Z-[(3aR,4R,5R,6aS)-3,3-difluorohexahydro-5-hydroxy-4-[(1E,3S,4S)-3-hydroxy-4-methyl-1-nonen-6-ynyl]-2H-cyclopenta[b]furan-2-ylidene]-pentanoic acid

CAS Number

788799-13-3

Molecular Formula

C22H30F2O5

Formula Weight

412.5

Purity

≥98%

Formulation

A solution in methyl acetate

SHIPPING & STORAGE

Storage

-20°C

Shipping

Wet ice in continental US; may vary elsewhere

Stability

≥ 1 year

Trade Information
  • Payment Terms
  • Days after Acceptance (DA), Cheque, Cash Advance (CA)
  • Supply Ability
  • 10 Per Day
  • Delivery Time
  • 10-15 Days
  • Sample Available
  • Yes
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • 500 µg 1MG 5MG
  • Main Export Market(s)
  • Asia
  • Main Domestic Market
  • All India

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