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AS-041164

AS-041164
AS-041164
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Product Code : SRGCC79
Brand Name : S.R GROUP CHEMICALS
Price And Quantity
  • Minimum Order Quantity
  • 1
  • Unit of Measure
  • Pack/Packs
  • Price
  • 5800-28400 INR
  • Price Range
  • 5800.00 - 28400.00 INR
Product Specifications
  • HS Code
  • 3821
  • Boiling point
  • REFER C.O.A MSDS
  • Smell
  • Stimulus
  • Shape
  • Crystal
  • Taste
  • Bitter
  • Appearance
  • POWDER
  • Shelf Life
  • 24 Months
  • Other Names
  • 5-(1,3-benzodioxol-5-ylmethylene)-2,4-thiazolidinedione
  • Melting Point
  • REFER C.O.A MSDS
  • Molecular Formula
  • C11H7NO4S
  • Physical Form
  • Solid
  • Structural Formula
  • C11H7NO4S
  • Molecular Weight
  • 249.2 Kilograms (kg)
  • Usage
  • R&D FORMULATION
  • Density
  • REFER C.O.A MSDS
  • Ph Level
  • REFER C.O.A MSDS
  • Classification
  • High Purity
  • Chemical Name
  • Other
  • CAS No
  • 6318-41-8
  • Type
  • TETRA HYDROXI STEAROL
  • Purity(%)
  • 98%
  • Color
  • WHITE
Product Description

DESCRIPTION

The phosphatidylinositol 3-kinases (PI3Ks) are lipid and protein kinases involved in diverse biological processes, including cell growth, migration, and metabolism.1 AS-041164 is a potent inhibitor of PI3K with selectivity for the class IB isoform PI3Kγ (IC50 = 70 nM), compared to PI3Kα (IC50 = 240 nM), PI3Kβ (IC50 = 1.45 μM), and PI3Kδ (IC50 =1.70 μM).2 When tested at 1.0 μM, it shows little or no activity against 38 other common kinases.2 When given orally to mice, AS-041164 shows a pharmacokinetic profile that is similar to the general PI3K inhibitor LY294002 but is three times more potent (ED50 = 27.4 mg/kg for AS-041164 versus 81.6 mg/kg for LY294002) in blocking neutrophil recruitment induced by RANTES.2

TECHNICAL INFORMATION

Formal Name

5-(1,3-benzodioxol-5-ylmethylene)-2,4-thiazolidinedione

CAS Number

6318-41-8

Molecular Formula

C11H7NO4S

Formula Weight

249.2

Purity

≥98%

Formulation

A crystalline solid

SHIPPING & STORAGE

Storage

-20°C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

≥ 2 years


Trade Information
  • Payment Terms
  • Days after Acceptance (DA), Cheque, Cash Advance (CA)
  • Supply Ability
  • 1O Per Day
  • Delivery Time
  • 10-15 Days
  • Sample Available
  • Yes
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • 5MG 10MG 25MG 50MG
  • Main Export Market(s)
  • Asia
  • Main Domestic Market
  • All India

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