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AS-041164 Chemical

AS-041164 Chemical

5800-28400 INR

Product Details:

  • Melting Point REFER C.O.A MSDS
  • Molecular Weight 249.2 Kilograms (kg)
  • Physical Form Solid
  • Boiling point REFER C.O.A MSDS
  • Other Names 5-(1,3-benzodioxol-5-ylmethylene)-2,4-thiazolidinedione
  • Taste Bitter
  • Shelf Life 24 Months
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AS-041164 Chemical Price And Quantity

  • 1 Pack
  • 5800-28400 INR
  • 5800.00 - 28400.00 INR

AS-041164 Chemical Product Specifications

  • 5-(1,3-benzodioxol-5-ylmethylene)-2,4-thiazolidinedione
  • High Purity
  • Stimulus
  • Other
  • Solid
  • 249.2 Kilograms (kg)
  • WHITE
  • Crystal
  • REFER C.O.A MSDS
  • REFER C.O.A MSDS
  • C11H7NO4S
  • R&D FORMULATION
  • 6318-41-8
  • 3821
  • TETRA HYDROXI STEAROL
  • C11H7NO4S
  • REFER C.O.A MSDS
  • Bitter
  • 98%
  • POWDER
  • 24 Months

AS-041164 Chemical Trade Information

  • Cash Advance (CA) Days after Acceptance (DA) Cheque
  • 10 Pack Per Day
  • 10-15 Days
  • Yes
  • Within a certain price range free samples are available
  • 5MG 10MG 25MG 50MG
  • Asia
  • All India

Product Description

DESCRIPTION

The phosphatidylinositol 3-kinases (PI3Ks) are lipid and protein kinases involved in diverse biological processes, including cell growth, migration, and metabolism.1 AS-041164 is a potent inhibitor of PI3K with selectivity for the class IB isoform PI3K (IC50 = 70 nM), compared to PI3K (IC50 = 240 nM), PI3K (IC50 = 1.45 M), and PI3K (IC50 =1.70 M).2 When tested at 1.0 M, it shows little or no activity against 38 other common kinases.2 When given orally to mice, AS-041164 shows a pharmacokinetic profile that is similar to the general PI3K inhibitor LY294002 but is three times more potent (ED50 = 27.4 mg/kg for AS-041164 versus 81.6 mg/kg for LY294002) in blocking neutrophil recruitment induced by RANTES.2

TECHNICAL INFORMATION

Formal Name

5-(1,3-benzodioxol-5-ylmethylene)-2,4-thiazolidinedione

CAS Number

6318-41-8

Molecular Formula

C11H7NO4S

Formula Weight

249.2

Purity

98%

Formulation

A crystalline solid

SHIPPING & STORAGE

Storage

 

-20C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

2 years


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