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Axitinib

Axitinib
Axitinib
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Product Code : SRGCC17
Brand Name : S.R GROUP CHEMICALS
Price And Quantity
  • Minimum Order Quantity
  • 1 Pack/Packs
  • Price
  • 6200-49600 INR
  • Price Range
  • 6200.00 - 49600.00 INR
Product Specifications
  • Boiling point
  • REFER C.O.A MSDS
  • Shape
  • Crystal
  • Taste
  • Bitter
  • Smell
  • Stimulus
  • Shelf Life
  • 24 Months
  • Appearance
  • POWDER
  • Molecular Formula
  • C22H18N4OS
  • Usage
  • R&D FORMULATION
  • Other Names
  • N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide
  • Molecular Weight
  • 386.5 Kilograms (kg)
  • Ph Level
  • REFER C.O.A MSDS
  • Density
  • REFER C.O.A MSDS
  • Melting Point
  • REFER C.O.A MSDS
  • Physical Form
  • Powder
  • Structural Formula
  • C22H18N4OS
  • Classification
  • High Purity
  • Chemical Name
  • Other
  • CAS No
  • 319460-85-0
  • Type
  • TETRA HYDROXI STEAROL
  • Purity(%)
  • 98%
  • Color
  • WHITE
Product Description

DESCRIPTION

Synonyms

  • AG-013736

Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively).1 Through its effects on VEGFRs, it causes regression of fenestrated, VEGFR-rich capillaries in tumors and normal tissue of mice, which is reversed following removal of the inhibitor.2,3,4 Axitinib has shown promise as a therapeutic in certain cancers and cancer models.5,6

TECHNICAL INFORMATION

Formal Name

N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide

CAS Number

319460-85-0

Synonyms

  • AG-013736

Molecular Formula

C22H18N4OS

Formula Weight

386.5

Purity

≥98%

Formulation

A crystalline solid

SHIPPING & STORAGE

Storage

-20°C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

≥ 2 years

Trade Information
  • Payment Terms
  • Days after Acceptance (DA), Cheque, Cash Advance (CA)
  • Delivery Time
  • 10-15 Days
  • Sample Available
  • Yes
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • 50MG 100MG 500MG
  • Main Export Market(s)
  • Central America
  • Main Domestic Market
  • All India

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