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Butaprost

Butaprost
Butaprost
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Product Code : SRGCC26
Brand Name : S.R GROUP CHEMICALS
Price And Quantity
  • Minimum Order Quantity
  • 1 Pack/Packs
  • Price
  • 11000-88000 INR
  • Price Range
  • 11000.00 - 88000.00 INR
Product Specifications
  • Appearance
  • POWDER
  • Melting Point
  • REFER C.O.A MSDS
  • Smell
  • Fragrant
  • Ph Level
  • REFER C.O.A MSDS
  • Molecular Formula
  • C24H40O5
  • HS Code
  • 3821
  • Boiling point
  • REFER C.O.A MSDS
  • Usage
  • R&D FORMAION
  • Physical Form
  • Powder
  • Taste
  • Bitter
  • Density
  • REFER C.O.A MSDS
  • Molecular Weight
  • 408.6 Kilograms (kg)
  • Shelf Life
  • 12 Months
  • Other Names
  • 9-oxo-11α,16R-dihydroxy-17-cyclobutyl-prost-13E-en-1-oic acid, methyl ester
  • Structural Formula
  • C24H40O5
  • Shape
  • Crystal
  • Classification
  • High Purity
  • Chemical Name
  • Other
  • CAS No
  • 69648-38-0
  • Type
  • TETRA HYDROXI STEAROL
  • Purity(%)
  • 98%
  • Color
  • WHITE
Product Description

DESCRIPTION

Synonyms

  • (±)-15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester
  • 15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester
  • TR 4978

Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells.1,2 Serious confusion as to the structure of butaprost was generated by Gardiner in 1986,3 when he reported that the epimer of butaprost showing this selective activity was the C-16 (R)-epimer (See reference 3 and Note). Butaprost binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor, and does not bind appreciably to any of the other murine EP receptors or DP, FP, IP, or TP receptors.4 The pharmacology of (R)-butaprost has not been carefully studied, but it is generally considered to be the less active epimer.5 (NOTE: In the Gardiner paper in the 1986 British Journal of Pharmacology, butaprost appears on page 46 where it is given the name TR 4979. The structure as drawn is incorrect, in that the author was using and referring to the more active C-16 epimer, which is actually 16(S). The structure on page 46 shows the structure as 16(R). It was not until the late 1990’s that careful studies both in the US and Japan correctly identified the actual configuration of C-16 in the compound called butaprost is 16(S).)3

ECHNICAL INFORMATION

Formal Name

9-oxo-11α,16R-dihydroxy-17-cyclobutyl-prost-13E-en-1-oic acid, methyl ester

CAS Number

69648-38-0

Synonyms

  • (±)-15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester
  • 15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester
  • TR 4978

Molecular Formula

C24H40O5

Formula Weight

408.6

Purity

≥98%

Formulation

A solution in methyl acetate

SHIPPING & STORAGE

Storage

-20°C

Shipping

Wet ice in continental US; may vary elsewhere

Stability

≥ 1 year


Trade Information
  • Payment Terms
  • Days after Acceptance (DA), Cheque, Cash Advance (CA)
  • Supply Ability
  • 10 Per Day
  • Delivery Time
  • 10-15 Days
  • Sample Available
  • Yes
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • 1MG 5MG 10MG
  • Main Export Market(s)
  • Asia
  • Main Domestic Market
  • All India

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