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Chidamide

Chidamide
Chidamide
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Product Code : SRGCC38
Brand Name : S.R GROUP CHEMICALS
  • Minimum Order Quantity
  • 1
  • Unit of Measure
  • Pack/Packs
  • Price Range
  • 3900.00 - 63400.00 INR
  • Price
  • 3900-63400 INR
  • Ph Level
  • REFER C.O.A MSDS
  • Other Names
  • N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-benzamide
  • Taste
  • Bitter
  • Shape
  • Crystal
  • Molecular Weight
  • 390.4 Kilograms (kg)
  • Appearance
  • SOLID
  • Smell
  • Stimulus
  • Physical Form
  • Solid
  • Usage
  • R&D FORMULATION
  • Structural Formula
  • C22H19FN4O2
  • Molecular Formula
  • C22H19FN4O2
  • Boiling point
  • REFER C.O.A MSDS
  • Melting Point
  • REFER C.O.A MSDS
  • Shelf Life
  • 24 Months
  • Density
  • REFER C.O.A MSDS
  • HS Code
  • 3821
  • Classification
  • High Purity
  • Chemical Name
  • Other
  • CAS No
  • 743420-02-2
  • Type
  • TETRA HYDROXI STEAROL
  • Purity(%)
  • 98%
  • Color
  • WHITE
  • Payment Terms
  • Days after Acceptance (DA), Cheque, Cash Advance (CA)
  • Supply Ability
  • 10 Per Day
  • Delivery Time
  • 10-15 Days
  • Sample Available
  • Yes
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • 1MG 5MG 10MG 25MG
  • Main Export Market(s)
  • Asia
  • Main Domestic Market
  • All India
Product Description

DESCRIPTION

Chidamide is a histone deacetylase inhibitor that increases histone H3 acetylation levels in LoVo and HT-29 colon cancer cells at concentrations as low as 4 µM.1 Additionally, chidamide affects the activation of oncogenic signaling kinases by dose-dependently reducing phosphorylated Akt, mTOR, p70S6k, Raf, and Erk1/2 protein expression in colon cancer cells.1 Furthermore, chidamide treatment dose-dependently upregulates p21 protein expression, downregulates Cdk4, and induces cell cycle arrest at the G0/G1 phase.1

ECHNICAL INFORMATION

Formal Name

N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-benzamide

CAS Number

743420-02-2

Molecular Formula

C22H19FN4O2

Formula Weight

390.4

Purity

≥98%

Formulation

A crystalline solid

SHIPPING & STORAGE

Storage

-20°C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

≥ 2 years



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