hydroxy Wortmannin

Next > >

hydroxy Wortmannin

Send Inquiry

Product Code : SRGCC18

Brand Name : S.R GROUP CHEMICAL

Price And Quantity

Minimum Order Quantity
1
Unit of Measure
Pack/Packs

Price Range
4600.00 - 64400.00 INR
Price
4600-64400 INR

Product Specifications

Shape
Crystal
Shelf Life
24 Months

Smell
Stimulus
Molecular Weight
430.4 Kilograms (kg)

Boiling point
REFER C.O.A MSDS
Physical Form
Powder

Melting Point
REFER C.O.A MSDS
Appearance
POWDER

Ph Level
REFER C.O.A MSDS
Structural Formula
C23H26O8

Density
REFER C.O.A MSDS
Other Names
17Î²-hydroxy-11-(acetyloxy)-1S,6bR,7,8,9aS,10,11R,11bR-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6,9-trione

Usage
R&D FORMULATION
Taste
Bitter

Molecular Formula
C23H26O8
Classification
High Purity

Chemical Name
Other
CAS No
58053-83-1

Type
TETRA HYDROXI STEAROL
Purity(%)
98%

Color
WHITE

Product Description

DESCRIPTION

17ÃŽÂ²-hydroxy Wortmannin is an analog of wortmannin. It irreversibly binds phosphoinositide 3-kinase (PI3K) and potently blocks fMLP-stimulated respiratory burst in neutrophils (IC50Â = 5 nM).1Â 17ÃŽÂ²-hydroxy Wortmannin inhibits recombinant PI3K and mTOR (IC50Â = 2.7 and 193 nM, respectively) and prevents the growth of LNCap prostate cancer cells (IC50Â = 1.46 ÃŽÂ¼M).2Â The 17-hydroxyl group has been used to further modify this compound,Â e.g.,Â by pegylation and conjugation with rapamycin.3,4

TECHNICAL INFORMATION

Formal Name

17ÃŽÂ²-hydroxy-11-(acetyloxy)-1S,6bR,7,8,9aS,10,11R,11bR-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6,9-trione

CAS Number

58053-83-1

Molecular Formula

C23H26O8

Formula Weight

430.4

Purity

Ã¢Â‰Â¥98%

Formulation

A crystalline solid

SHIPPING & STORAGE

Storage

-20Ã‚Â°C

Shipping

Room temperatureÂ in continental US; may vary elsewhere

Stability

Ã¢Â‰Â¥ 2 years

Trade Information