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hydroxy Wortmannin

hydroxy Wortmannin
hydroxy Wortmannin
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Product Code : SRGCC18
Brand Name : S.R GROUP CHEMICAL
Price And Quantity
  • Minimum Order Quantity
  • 1
  • Unit of Measure
  • Pack/Packs
  • Price Range
  • 4600.00 - 64400.00 INR
  • Price
  • 4600-64400 INR
Product Specifications
  • Shape
  • Crystal
  • Shelf Life
  • 24 Months
  • Smell
  • Stimulus
  • Molecular Weight
  • 430.4 Kilograms (kg)
  • Boiling point
  • REFER C.O.A MSDS
  • Physical Form
  • Powder
  • Melting Point
  • REFER C.O.A MSDS
  • Appearance
  • POWDER
  • Ph Level
  • REFER C.O.A MSDS
  • Structural Formula
  • C23H26O8
  • Density
  • REFER C.O.A MSDS
  • Other Names
  • 17β-hydroxy-11-(acetyloxy)-1S,6bR,7,8,9aS,10,11R,11bR-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6,9-trione
  • Usage
  • R&D FORMULATION
  • Taste
  • Bitter
  • Molecular Formula
  • C23H26O8
  • Classification
  • High Purity
  • Chemical Name
  • Other
  • CAS No
  • 58053-83-1
  • Type
  • TETRA HYDROXI STEAROL
  • Purity(%)
  • 98%
  • Color
  • WHITE
Product Description

DESCRIPTION

17β-hydroxy Wortmannin is an analog of wortmannin. It irreversibly binds phosphoinositide 3-kinase (PI3K) and potently blocks fMLP-stimulated respiratory burst in neutrophils (IC50 = 5 nM).1 17β-hydroxy Wortmannin inhibits recombinant PI3K and mTOR (IC50 = 2.7 and 193 nM, respectively) and prevents the growth of LNCap prostate cancer cells (IC50 = 1.46 μM).2 The 17-hydroxyl group has been used to further modify this compound, e.g., by pegylation and conjugation with rapamycin.3,4

TECHNICAL INFORMATION

Formal Name

17β-hydroxy-11-(acetyloxy)-1S,6bR,7,8,9aS,10,11R,11bR-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6,9-trione

CAS Number

58053-83-1

Molecular Formula

C23H26O8

Formula Weight

430.4

Purity

≥98%

Formulation

A crystalline solid

SHIPPING & STORAGE

Storage

-20°C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

≥ 2 years

Trade Information
  • Payment Terms
  • Days after Acceptance (DA), Cheque, Cash Advance (CA)
  • Supply Ability
  • 10 Per Day
  • Delivery Time
  • 10-15 Days
  • Sample Available
  • Yes
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • 500 µg 1 mg 5 mg 10 mg
  • Main Export Market(s)
  • Asia
  • Main Domestic Market
  • All India

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