hydroxy Wortmannin

Next > >

hydroxy Wortmannin

Send Inquiry

Product Code : SRGCC18

Brand Name : S.R GROUP CHEMICAL

Price And Quantity

Minimum Order Quantity
1
Unit of Measure
Pack/Packs

Price Range
4600.00 - 64400.00 INR
Price
4600-64400 INR

Product Specifications

Ph Level
REFER C.O.A MSDS
Boiling point
REFER C.O.A MSDS

Usage
R&D FORMULATION
Structural Formula
C23H26O8

Melting Point
REFER C.O.A MSDS
Smell
Stimulus

Other Names
17β-hydroxy-11-(acetyloxy)-1S,6bR,7,8,9aS,10,11R,11bR-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6,9-trione
Physical Form
Powder

Appearance
POWDER
Shape
Crystal

Taste
Bitter
Shelf Life
24 Months

Molecular Weight
430.4 Kilograms (kg)
Density
REFER C.O.A MSDS

Molecular Formula
C23H26O8
Classification
High Purity

Chemical Name
Other
CAS No
58053-83-1

Type
TETRA HYDROXI STEAROL
Purity(%)
98%

Color
WHITE

Product Description

DESCRIPTION

17ÃŽÂ²-hydroxy Wortmannin is an analog of wortmannin. It irreversibly binds phosphoinositide 3-kinase (PI3K) and potently blocks fMLP-stimulated respiratory burst in neutrophils (IC50Â = 5 nM).1Â 17ÃŽÂ²-hydroxy Wortmannin inhibits recombinant PI3K and mTOR (IC50Â = 2.7 and 193 nM, respectively) and prevents the growth of LNCap prostate cancer cells (IC50Â = 1.46 ÃŽÂ¼M).2Â The 17-hydroxyl group has been used to further modify this compound,Â e.g.,Â by pegylation and conjugation with rapamycin.3,4

TECHNICAL INFORMATION

Formal Name

17ÃŽÂ²-hydroxy-11-(acetyloxy)-1S,6bR,7,8,9aS,10,11R,11bR-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6,9-trione

CAS Number

58053-83-1

Molecular Formula

C23H26O8

Formula Weight

430.4

Purity

Ã¢Â‰Â¥98%

Formulation

A crystalline solid

SHIPPING & STORAGE

Storage

-20Ã‚Â°C

Shipping

Room temperatureÂ in continental US; may vary elsewhere

Stability

Ã¢Â‰Â¥ 2 years

Trade Information