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Icariin

Icariin
Icariin
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Product Code : SRGCC77
Brand Name : S.R GROUP CHEMICALS
Price And Quantity
  • Minimum Order Quantity
  • 1
  • Unit of Measure
  • Pack/Packs
  • Price Range
  • 6100.00 - 106800.00 INR
  • Price
  • 6100-106800 INR
Product Specifications
  • Structural Formula
  • C33H40O15
  • Shelf Life
  • 24 Months
  • Other Names
  • 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
  • Ph Level
  • REFER C.O.A MSDS
  • Melting Point
  • REFER C.O.A MSDS
  • Boiling point
  • REFER C.O.A MSDS
  • Density
  • REFER C.O.A MSDS
  • Physical Form
  • Solid
  • Taste
  • Bitter
  • HS Code
  • 3821
  • Usage
  • R&D FORMULATION
  • Shape
  • Crystal
  • Smell
  • Stimulus
  • Molecular Weight
  • 676.6 Kilograms (kg)
  • Appearance
  • POWDER
  • Molecular Formula
  • C33H40O15
  • Classification
  • High Purity
  • Chemical Name
  • Other
  • CAS No
  • 489-32-7
  • Type
  • TETRA HYDROXI STEAROL
  • Purity(%)
  • 97%
  • Color
  • WHITE
Product Description

DESCRIPTION

The cyclic nucleotide second messenger guanosine 3’5’-cyclic monophosphate (cGMP) is an important mediator of signal transduction and hence a wide range of cellular processes. It is generated by soluble- and particulate-type guanylyl cyclase and degraded via members of the phosphodiesterase (PDE) protein family. Icariin, the active component of the Chinese medicinal plant E. brevicornum, is an inhibitor of human recombinant PDE5 with an IC50 value of 5.9 µM.1 It is a prenylated flavonol that has been used to treat erectile dysfunction and has been shown to have anti-cancer and antioxidant activity.2 At a concentration of 1 x 107 mol/L, icariin induces differentiation of cardiomyocytes and upregulates the expression of cardiac genes.3 At 20 µg/ml, icariin increases the proliferation and differentiation of cultured human osteoblasts, which appears to be mediated in part by upregulating bone morphogenetic protein 2 mRNA.4

TECHNICAL INFORMATION

Formal Name

3-[(6-deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one

CAS Number

489-32-7

Molecular Formula

C33H40O15

Formula Weight

676.6

Purity

≥97%

Formulation

A crystalline solid

SHIPPING & STORAGE

Storage

-20°C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

≥ 2 years


Trade Information
  • Payment Terms
  • Days after Acceptance (DA), Cheque, Cash Advance (CA)
  • Supply Ability
  • 10 Per Day
  • Delivery Time
  • 10-15 Days
  • Sample Available
  • Yes
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • 1G 5G 10G 25G
  • Main Export Market(s)
  • Asia
  • Main Domestic Market
  • All India

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