Icariin

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Icariin

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Product Code : SRGCC77

Brand Name : S.R GROUP CHEMICALS

Price And Quantity

Minimum Order Quantity
1 Pack
Price
6100-106800 INR

Product Specifications

Boiling point
REFER C.O.A MSDS
Usage
R&D FORMULATION

Melting Point
REFER C.O.A MSDS
HS Code
3821

Shelf Life
24 Months
Ph Level
REFER C.O.A MSDS

Shape
Crystal
Density
REFER C.O.A MSDS Gram per cubic centimeter(g/cm3)

Smell
Stimulus
Molecular Formula
C33H40O15

Molecular Weight
676.6 Kilograms (kg)
Appearance
POWDER

Physical Form
Solid
Structural Formula
C33H40O15

Other Names
3-[(6-deoxy--L-mannopyranosyl)oxy]-7-(-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
Taste
Bitter

Classification
High Purity
Chemical Name
Other

CAS No
489-32-7
Type
TETRA HYDROXI STEAROL

Purity(%)
97%
Color
WHITE

Product Description

The cyclic nucleotide second messenger guanosine 3 -5 -cyclic monophosphate (cGMP) is an important mediator of signal transduction and hence a wide range of cellular processes. It is generated by soluble- and particulate-type guanylyl cyclase and degraded via members of the phosphodiesterase (PDE) protein family. Icariin, the active component of the Chinese medicinal plant E. brevicornum, is an inhibitor of human recombinant PDE5 with an IC50 value of 5.9 M.1 It is a prenylated flavonol that has been used to treat and has been shown to have and antioxidant activity.2 At a concentration of 1 x 107 mol/L, icariin induces differentiation of cardiomyocytes and upregulates the expression of cardiac genes.3 At 20 g/ml, icariin increases the proliferation and differentiation of cultured human osteoblasts, which appears to be mediated in part by upregulating bone morphogenetic protein 2 mRNA.4

TECHNICAL INFORMATION

Formal Name

3-[(6-deoxy- -L-mannopyranosyl)oxy]-7-( -D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one

CAS Number

489-32-7

Molecular Formula

C33H40O15

Formula Weight

676.6

Purity

97%

Formulation

A crystalline solid

SHIPPING & STORAGE

Storage

-20 C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

2 years

Trade Information