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JZL 195

JZL 195
JZL 195
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Product Code : SRGCC46
Brand Name : S.R GROUP CHEMICALS
Price And Quantity
  • Minimum Order Quantity
  • 1 Pack/Packs
  • Price Range
  • 4800.00 - 67200.00 INR
  • Price
  • 4800-67200 INR
Product Specifications
  • Smell
  • Stimulus
  • Appearance
  • POWDER
  • Molecular Formula
  • C24H23N3O5
  • Density
  • REFER C.O.A MSDS
  • Structural Formula
  • C24H23N3O5
  • HS Code
  • 3821
  • Usage
  • R&D FORMULATION
  • Melting Point
  • REFER C.O.A MSDS
  • Other Names
  • 4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate
  • Molecular Weight
  • 433.5 Kilograms (kg)
  • Physical Form
  • Powder
  • Ph Level
  • REFER C.O.A MSDS
  • Taste
  • Bitter
  • Shelf Life
  • 24 Months
  • Boiling point
  • REFER C.O.A MSDS
  • Shape
  • Crystal
  • Classification
  • High Purity
  • Chemical Name
  • Other
  • CAS No
  • 1210004-12-8
  • Type
  • TETRA HYDROXI STEAROL
  • Purity(%)
  • 98%
  • Color
  • WHITE
Product Description

DESCRIPTION

Fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) mediate the hydrolysis of the endocannabinoids arachidonoyl ethanolamide (AEA) and 2-arachidonoylglycerol (2-AG), respectively. JZL 195 is a potent inhibitor of both FAAH and MAGL (IC50s = 2 and 4 nM, respectively).1 It poorly inhibits neuropathy target esterase and ABHD6 and does not inhibit other brain serine hydrolases. JZL 195 displays time-dependent inhibition of FAAH and MAGL in vivo, consistent with a covalent mechanism of activation.1 The in vivo inhibitory actions of JZL 195 against FAAH and MAGL are comparable to those of the selective inhibitors PF-3845 (Item No. 13279) and JZL 184 (Item No. 13158), respectively.1 Through its inhibitory actions, JZL 195 simultaneously augments brain levels of AEA and 2-AG, producing antinociceptive, cataleptic, and hypomotility effects like those produced by direct CB1agonists.1

TECHNICAL INFORMATION

Formal Name

4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate

CAS Number

1210004-12-8

Molecular Formula

C24H23N3O5

Formula Weight

433.5

Purity

≥98%

Formulation

A crystalline solid

λmax

273 nm

SHIPPING & STORAGE

Storage

-20°C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

≥ 2 years


Trade Information
  • Payment Terms
  • Days after Acceptance (DA), Cheque, Cash Advance (CA)
  • Supply Ability
  • 10 Per Day
  • Delivery Time
  • 10-15 Days
  • Sample Available
  • Yes
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • 5MG 10MG 50MG 100MG
  • Main Export Market(s)
  • Asia
  • Main Domestic Market
  • All India

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