Methysticin

DESCRIPTION
Synonyms

    Kavatin
    d-Methysticin
    NSC 112158

Methysticin is a natural kavalactone from the kava plant, P. methysticum. It enhances the binding of bicuculline methochloride at the γ-amino butyric acid (GABA) receptor GABAA at 0.1 µM.1 Methysticin inhibits the cytochrome P450 (CYP) isoforms CYP2C9 and CYP2D6.2

TECHNICAL INFORMATION
Formal Name   : (6R)-6-[(1E)-2-(1,3-benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one
CAS Number  :  495-85-2
Synonyms    

    Kavatin
    d-Methysticin
    NSC 112158

• Molecular Formula :   C15H14O5
• Formula Weight  :  274.3
• Purity  :  ≥98%
• Formulation  :  A crystalline solid
• λmax  ;  208, 225, 265, 306 nm
• SMILES  ;  COC(C[C@H](/C=C/C1=CC=C(OCO2)C2=C1)O3)=CC3=O
• InChI Code  :  1S/C15H14O5/c1-17-12-7-11(20-15(16)8-12)4-2-10-3-5-13-14(6-10)19-9-18-13/h2-6,8,11H,7,9H2,1H3/b4-2+/t11-/m0/s1
• InChI Key  ;  GTEXBOVBADJOQH-FWEMWIAWSA-N

WARNING - This product is not for human or veterinary use.

SHIPPING & STORAGE

• Storage :   -20°C
• Shipping  :  Wet ice in continental US; may vary elsewhere
• Stability  :  As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored prop