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Oligomycin E (CAS 110231-34-0)

Oligomycin E (CAS 110231-34-0)

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Product Description

DESCRIPTION
Synonyms

26-hydroxy-28-oxo-Oligomycin A


Oligomycin E is a minor metabolite of the oligomycin complex (Item No. 11341) produced by several species of Streptomyces. It exhibits relatively weak antifungal activity compared to other oligomycins, yet is active against Gram-positive bacteria and demonstrates strong antitumor activity against HeLa cells (IC50 = 14 ng/ml).1
TECHNICAL INFORMATION
Formal Name    (1R,2'S,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28R,29R)-22-ethyl-5',6'-dihydro-7,11,14,15,28-pentahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,3',9,13(4'H)-tetrone
CAS Number    110231-34-0
Synonyms    

    26-hydroxy-28-oxo-Oligomycin A

  • Molecular Formula    C45H72O13
  • Formula Weight    821.1
  • Purity    95%
  • Formulation    A lyophilisate
  • SMILES    C[C@]1(O)[C@@](C(C[C@@H]2C)=O)(O[C@H]([C@]([H])([C@H]1OC(/C=C/[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)[C@@H](O)[C@H](C)C3=O)=O)=O)C)CC[C@@]([H])(CC)/C=C/C=C/C[C@@H](C)[C@H](O)[C@@]3(C)O)O[C@H]2C[C@@H](C)O
  • InChI Code    1S/C45H72O13/c1-12-32-17-15-13-14-16-25(3)40(52)43(10,54)41(53)31(9)39(51)30(8)38(50)29(7)37(49)24(2)18-21-36(48)56-42-28(6)33(20-19-32)57-45(44(42,11)55)35(47)22-26(4)34(58-45)23-27(5)46/h13-15,17-18,21,24-34,37,39-40,42,46,49,51-52,54-55H,12,
  • InChI Key    UWEZMQMMPORRMH-BOCHHXLBSA-N


WARNING - This product is not for human or veterinary use.

SHIPPING & STORAGE

  • Storage    -20C
  • Shipping    Wet ice in continental US; may vary elsewhere
  • Stability    As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly

 

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