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PX 866

PX 866
PX 866
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Product Code : SRGCC60
Brand Name : S.R GROUP CHEMICALS
Price And Quantity
  • Minimum Order Quantity
  • 1
  • Unit of Measure
  • Pack/Packs
  • Price Range
  • 5900.00 - 41300.00 INR
  • Price
  • 5900-41300 INR
Product Specifications
  • Boiling point
  • REFER C.O.A MSDS
  • Melting Point
  • REFER C.O.A MSDS
  • HS Code
  • 3821
  • Appearance
  • POWDER
  • Ph Level
  • REFER C.O.A MSDS
  • Molecular Formula
  • C29H35NO8
  • Shape
  • Crystal
  • Molecular Weight
  • 525.6 Kilograms (kg)
  • Usage
  • R&D FORMULATION
  • Structural Formula
  • C29H35NO8
  • Other Names
  • (1E,4S,4aR,5R,6aS,9aR)-5-(acetyloxy)-1-[(di-2-propen-1-ylamino)methylene]-4,4a,5,6,6a,8,9,9a-octahydro-11-hydroxy-4-(methoxymethyl)-4a,6a-dimethyl-cyclopenta[5,6]naphtho[1,2-c]pyran-2,7,10(1H)-trione
  • Taste
  • Bitter
  • Physical Form
  • Solid
  • Shelf Life
  • 24 Months
  • Density
  • REFER C.O.A MSDS
  • Smell
  • Stimulus
  • Classification
  • High Purity
  • Chemical Name
  • Other
  • CAS No
  • 502632-66-8
  • Type
  • TETRA HYDROXI STEAROL
  • Purity(%)
  • 98%
  • Color
  • WHITE
Product Description

DESCRIPTION

PX 866 is a ring-opened analog of wortmannin (Item No. 10010591) that potently and irreversibly inhibits PI3K (IC50 = 0.1-88 nM).1,2 It less potently blocks the activity of mammalian target of rapamycin (mTOR, IC50 = 3.1 µM).2 PX 866 exhibits single agent in vivo anti-tumor activity and increases the anti-tumor effects of cisplatin and radiation treatment.1,3 In cancer cells grown in three-dimensional cultures, PX 866 reduces cell growth and motility without causing cytotoxicity.4 Consistent with having cytostatic effects, PX 866 dosing is associated with prolonged stable disease in cancer patients.5

TECHNICAL INFORMATION

Formal Name

(1E,4S,4aR,5R,6aS,9aR)-5-(acetyloxy)-1-[(di-2-propen-1-ylamino)methylene]-4,4a,5,6,6a,8,9,9a-octahydro-11-hydroxy-4-(methoxymethyl)-4a,6a-dimethyl-cyclopenta[5,6]naphtho[1,2-c]pyran-2,7,10(1H)-trione

CAS Number

502632-66-8

Molecular Formula

C29H35NO8

Formula Weight

525.6

Purity

≥98%

Formulation

A crystalline solid

SHIPPING & STORAGE

Storage

-20°C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

≥ 2 years

Trade Information
  • Payment Terms
  • Days after Acceptance (DA), Cheque, Cash Advance (CA)
  • Supply Ability
  • 10 Per Day
  • Delivery Time
  • 10-15 Days
  • Sample Available
  • Yes
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • 1MG 5MG 10MG
  • Main Export Market(s)
  • Asia
  • Main Domestic Market
  • All India

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