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Tubacin

Tubacin
Tubacin
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Product Code : SRGCC34
Brand Name : S.R GROUP CHEMICALS
Price And Quantity
  • Minimum Order Quantity
  • 1
  • Unit of Measure
  • Pack/Packs
  • Price
  • 8500-27600 INR
  • Price Range
  • 8500.00 - 27600.00 INR
Product Specifications
  • Molecular Weight
  • 721.9 Kilograms (kg)
  • Density
  • REFER C.O.A MSDS
  • Structural Formula
  • C41H43N3O7S
  • Appearance
  • SOLID
  • Boiling point
  • REFER C.O.A MSDS
  • HS Code
  • 3821
  • Shape
  • Crystal
  • Physical Form
  • Solid
  • Other Names
  • N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide
  • Melting Point
  • REFER C.O.A MSDS
  • Shelf Life
  • 24 Months
  • Ph Level
  • REFER C.O.A MSDS
  • Molecular Formula
  • C41H43N3O7S
  • Taste
  • Bitter
  • Usage
  • R&D FORMULATION
  • Classification
  • High Purity
  • Chemical Name
  • Other
  • CAS No
  • 537049-40-4
  • Type
  • TETRA HYDROXI STEAROL
  • Purity(%)
  • 90%
  • Color
  • WHITE
Product Description

DESCRIPTION

Tubacin is a tubulin acetylation inducer that selectively inhibits histone deacetylase (HDAC) 6 (IC50 = 4 nM).1 In comparison, it demonstrates at least 300-fold selectivity against all other HDAC isoforms (IC50s range from 1.3-17.3 μM).1 Tubacin induces α-tubulin hyperacetylation at 2.5 μM in primary cortical neuron cultures.1 Tubacin inhibition of HDAC6 has been used as a biochemical tool to control microtubule-dependent intracellular trafficking, to manipulate the aggresome formation of misfolded proteins in certain diseases, and to study the dynamics of cellular adhesion.2,3,4

TECHNICAL INFORMATION

Formal Name

N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide

CAS Number

537049-40-4

Molecular Formula

C41H43N3O7S

Formula Weight

721.9

Purity

≥90%

Formulation

A crystalline solid

λmax

222, 240, 299 nm

SHIPPING & STORAGE

Storage

-20°C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

≥ 2 years


Trade Information
  • Payment Terms
  • Days after Acceptance (DA), Cheque, Cash Advance (CA)
  • Supply Ability
  • 10 Per Day
  • Delivery Time
  • 10-15 Days
  • Sample Available
  • Yes
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • 1MG 5MG
  • Main Export Market(s)
  • Asia
  • Main Domestic Market
  • All India

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