Tubacin Chemical

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Tubacin Chemical

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Product Code : SRGCC34

Brand Name : S.R GROUP CHEMICALS

Price And Quantity

Minimum Order Quantity
1 Pack
Price Range
8500.00 - 27600.00 INR

Price
8500-27600 INR

Product Specifications

Appearance
SOLID
Usage
R&D FORMULATION

Shape
Crystal
Shelf Life
24 Months

Melting Point
REFER C.O.A MSDS
Ph Level
REFER C.O.A MSDS

Molecular Formula
C41H43N3O7S
HS Code
3821

Physical Form
Solid
Taste
Bitter

Molecular Weight
721.9 Kilograms (kg)
Boiling point
REFER C.O.A MSDS

Structural Formula
C41H43N3O7S
Other Names
N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide

Classification
High Purity
Chemical Name
Other

CAS No
537049-40-4
Type
TETRA HYDROXI STEAROL

Purity(%)
90%
Color
WHITE

Product Description

DESCRIPTION

Tubacin is a tubulin acetylation inducer that selectively inhibits histone deacetylase (HDAC) 6 (IC50 = 4 nM).1 In comparison, it demonstrates at least 300-fold selectivity against all other HDAC isoforms (IC50s range from 1.3-17.3 ÃŽ¼M).1 Tubacin induces ÃŽ±-tubulin hyperacetylation at 2.5 ÃŽ¼M in primary cortical neuron cultures.1 Tubacin inhibition of HDAC6 has been used as a biochemical tool to control microtubule-dependent intracellular trafficking, to manipulate the aggresome formation of misfolded proteins in certain diseases, and to study the dynamics of cellular adhesion.2,3,4

TECHNICAL INFORMATION

Formal Name

N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide

CAS Number

537049-40-4

Molecular Formula

C41H43N3O7S

Formula Weight

721.9

Purity

Ã¢‰¥90%

Formulation

A crystalline solid

ÃŽ»max

222, 240, 299 nm

SHIPPING & STORAGE

Storage

-20Ã‚°C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

Ã¢‰¥ 2 years

Trade Information