Tubacin Chemical

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Tubacin Chemical

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Product Code : SRGCC34

Brand Name : S.R GROUP CHEMICALS

Price And Quantity

Minimum Order Quantity
1 Pack
Price Range
8500.00 - 27600.00 INR

Price
8500-27600 INR

Product Specifications

Shelf Life
24 Months
Physical Form
Solid

Boiling point
REFER C.O.A MSDS
Other Names
N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide

Molecular Formula
C41H43N3O7S
Taste
Bitter

Melting Point
REFER C.O.A MSDS
Usage
R&D FORMULATION

Structural Formula
C41H43N3O7S
Ph Level
REFER C.O.A MSDS

Shape
Crystal
HS Code
3821

Molecular Weight
721.9 Kilograms (kg)
Appearance
SOLID

Classification
High Purity
Chemical Name
Other

CAS No
537049-40-4
Type
TETRA HYDROXI STEAROL

Purity(%)
90%
Color
WHITE

Product Description

DESCRIPTION

Tubacin is a tubulin acetylation inducer that selectively inhibits histone deacetylase (HDAC) 6 (IC50 = 4 nM).1 In comparison, it demonstrates at least 300-fold selectivity against all other HDAC isoforms (IC50s range from 1.3-17.3 ÃŽ¼M).1 Tubacin induces ÃŽ±-tubulin hyperacetylation at 2.5 ÃŽ¼M in primary cortical neuron cultures.1 Tubacin inhibition of HDAC6 has been used as a biochemical tool to control microtubule-dependent intracellular trafficking, to manipulate the aggresome formation of misfolded proteins in certain diseases, and to study the dynamics of cellular adhesion.2,3,4

TECHNICAL INFORMATION

Formal Name

N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide

CAS Number

537049-40-4

Molecular Formula

C41H43N3O7S

Formula Weight

721.9

Purity

Ã¢‰¥90%

Formulation

A crystalline solid

ÃŽ»max

222, 240, 299 nm

SHIPPING & STORAGE

Storage

-20Ã‚°C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

Ã¢‰¥ 2 years

Trade Information