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WZ811

WZ811
WZ811
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Product Code : SRGCC67
Brand Name : S.R GROUP CHEMICALS
Price And Quantity
  • Minimum Order Quantity
  • 1
  • Unit of Measure
  • Pack/Packs
  • Price Range
  • 1400.00 - 24500.00 INR
  • Price
  • 1400-24500 INR
Product Specifications
  • Melting Point
  • REFER C.O.A MSDS
  • Molecular Formula
  • C18H18N4
  • Density
  • REFER C.O.A MSDS
  • Molecular Weight
  • 290.4 Kilograms (kg)
  • Structural Formula
  • C18H18N4
  • Taste
  • Bitter
  • Other Names
  • N1,N4-di-2-pyridinyl-1,4-benzenedimethanamine
  • HS Code
  • 3821
  • Physical Form
  • Solid
  • Boiling point
  • REFER C.O.A MSDS
  • Smell
  • Stimulus
  • Shape
  • Crystal
  • Appearance
  • POWDER
  • Ph Level
  • REFER C.O.A MSDS
  • Usage
  • R&D FORMULATION
  • Shelf Life
  • 24 Months
  • Classification
  • High Purity
  • Chemical Name
  • Other
  • CAS No
  • 55778-02-4
  • Type
  • TETRA HYDROXI STEAROL
  • Purity(%)
  • 95%
  • Color
  • WHITE
Product Description

DESCRIPTION

The CXC chemokine receptor-4 (CXCR4) is a G protein-coupled receptor that is specific for stromal cell-derived factor-1 (SDF-1/ CXCL12). Activation of CXCR4 promotes homing of hematopoietic stem cells, chemotaxis and quiescence of lymphocytes, and growth and metastasis of certain cancer cell types. Moreover, CXCR4 on CD4+ T-cells is used by CXCR4-selective HIV forms as a gateway for T-cell infection. WZ811 is a potent inhibitor of binding of an SDF-1 peptide mimic to CXCR4 (EC50 = 0.3 nM).1 It prevents SDF-1/CXCL12-mediated modulation of cAMP (EC50 = 1.2 nM) in cells and blocks SDF-1-induced Matrigel™ invasion by MDA-MB-231 human breast adenocarcinoma cells (EC50 = 5.2 nM).1 The effectiveness of WZ811 in animals remains to be elucidated.

TECHNICAL INFORMATION

Formal Name

N1,N4-di-2-pyridinyl-1,4-benzenedimethanamine

CAS Number

55778-02-4

Molecular Formula

C18H18N4

Formula Weight

290.4

Purity

≥95%

Formulation

A crystalline solid

SHIPPING & STORAGE

Storage

-20°C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

≥ 2 years

Trade Information
  • Payment Terms
  • Cheque, Cash Advance (CA)
  • Supply Ability
  • 10 Per Day
  • Delivery Time
  • 10-15 Days
  • Sample Available
  • Yes
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • 1MG 5MG 10MG 25MG
  • Main Export Market(s)
  • Asia
  • Main Domestic Market
  • All India

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