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Fumagillin

Fumagillin
Fumagillin
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Product Code : 2368
Brand Name : BioVision
Product Description

Fumagillin

An angiogenesis inhibitor

 FOR REQUIREMENT BULCK SPECIAL PRICE WILL BE GIVEN

                            V.S.P , B.P GRADE 

SKU: 2368 

Fumagillin is a meroterpenoid antibiotic isolated from Aspergillus fumigatus. An anticancer, antimicrobial, antimalarial and amoebicidal compound. Potent, selective and covalent inhibitor of methionine aminopeptidase-2 (MetAP2). Anti-angiogenic by impairing the growth of endothelial cells and altering gene expression. Inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo. 

 

Size1 mg
SKU+Size2368-1
Alternate NameAmebacilin; Fugilin; Fumidil; Fumadil B; NSC9168; U5762
AppearanceOff-white solid
CAS #23110-15-8
Molecular FormulaC₂₆H₃₄O₇
Molecular Weight458.54
Purity≥98% by NMR
SolubilityEthanol (~ 1 mg/ml)
SMILESCC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C
InChiInChI=1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20-,23-,24-,25+,26+/m1/s1
InChi KeyNGGMYCMLYOUNGM-CSDLUJIJSA-N
PubChem CID6917655
MDL NumberMFCD03990453
HandlingProtect from light and moisture
Storage Conditions-20°C
Shipping ConditionsGel Pack
USAGEFor Research Use Only! Not For Use in Humans.

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