
CAS Number : 65391-42-6
Empirical Formula (Hill Notation) : C16H24N2O4 HCl
Molecular Weight : 344.83
Beilstein Registry Number : 4628066
MDL number : MFCD00058004
PubChem Substance ID : 24278278
1, 5 mg in glass bottle
10, 25 mg in poly bottle
100 mg in glass bottle
Solubility testing in water at 25 mg/ml yields a clear solution. Stock solutions at 1 mM are expected to be stable at least one month stored at -20 C.
A metalloprotease inhibitor selective for aminopeptidase. Bestatin is a competitive and specific inhibitor of leucine aminopeptidase, aminopeptidase B, and triamino peptidase. It inhibits aminopeptidase B at 60 nM (using arginine--naphthylamide as substrate) and leucine aminopeptidase at 20 nM (leucine--naphthylamide as substrate). It showed no inhibition of aminopeptidase A, trypsin, chymotrypsin, elastase, papain, pepsin, or themolysin. It offers promise as a novel analgesic because it protects endogenous peptides against degradation.
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