G418 (Geneticin)
G418 (Geneticin)

G418 (Geneticin)

MOQ : 50 Packs

G418 (Geneticin) Specification

  • Usage
  • Inhibits protein synthesis in susceptible prokaryotic and eukaryotic cells
  • Ph Level
  • pH 4.5 - 5.5 (50mg/mL H2O)
  • Structural Formula
  • Available on request
  • Melting Point
  • 218 - 222C (dec.)
  • Other Names
  • Geneticin
  • Taste
  • Bitter
  • Storage
  • 2-8C, protect from light and moisture
  • Molecular Formula
  • C20H40N4O10H2SO4
  • Shape
  • Crystalline
  • Shelf Life
  • 24 Months
  • Appearance
  • Powder
  • Molecular Weight
  • 692.7 g/mol
  • HS Code
  • 29419090
  • Physical Form
  • Solid
  • Application
  • Cell culture; Selection of genetically engineered cells
  • Smell
  • Odorless
  • Poisonous
  • Yes
  • Grade
  • Cell Culture Grade
  • Classification
  • Biochemical; Antibiotic
  • Chemical Name
  • G418 Sulfate
  • CAS No
  • 108321-42-2
  • Type
  • Antibiotic; Aminoglycoside
  • Purity(%)
  • >98%
  • Color
  • White to Off-White
  • Inhibitory Concentration
  • Effective at 200-500 g/mL for most cells
  • Loss on Drying
  • <5%
  • Storage Conditions
  • Store in tightly closed containers at 2-8C
  • Packing
  • Bottle, 1g, 5g, 10g, custom packing available
  • Solubility
  • Soluble in water (50mg/mL)
  • Stability
  • Stable under recommended storage conditions
 
 

About G418 (Geneticin)



S.R. GROUP is a leader in the production of selection antibiotics. Our state-of-the-art facilities allow us to produce large quantities of high quality, endotoxin-free antibiotics with purity levels exceeding 95%.

As we manufacture our products, we are able to offer the best prices on the market.

Ready-to-use Cell Culture Tested Solutions - No weighing needed - Our antibiotics are available in solution filtered to sterility for customer convenience and validated for cell culture usage.

An Excellent Choice of Antibiotics for Selection in Both Mammalian cells and E. coli - Matches up to the antibiotic resistance genes carried by plasmids, built for selection in both mammalian and bacteria cells.


Products

Blasticidin Selective antibiotic for the bsr, bls, or BSD genesZeocin Selective antibiotic for the Sh ble genePuromycin Selective antibiotic for the pac geneG418 (Geneticin) Selective antibiotic for the neo geneHygromycin B Gold Selective antibiotic for the hph gene - Hygromycin B High purityPhleomycin Selective antibiotic for the Sh ble gene



Precise Application in Cell Culture

G418 Sulfate is widely utilized for the selection of genetically engineered cells. By inhibiting protein synthesis, it allows researchers to isolate and grow only those cells that have successfully incorporated desired genetic modifications, improving experimental reliability and efficiency.


Quality and Packaging Options

Offered at >98% purity and cell culture grade, G418 comes packaged in 1g, 5g, 10g bottles, with custom packing available to meet diverse requirements. Its crystalline, white to off-white powder form ensures easy handling and precise dosing during laboratory procedures.

FAQs of G418 (Geneticin):


Q: How should G418 (Geneticin) be stored to maintain stability?

A: G418 should be stored in tightly closed containers at 28C, protected from light and moisture, to ensure stability and preserve its activity for up to 24 months.

Q: What is the recommended concentration of G418 for effective cell selection?

A: For most cell types, G418 is effective at concentrations between 200500 g/mL, inhibiting protein synthesis and enabling the selection of genetically engineered cells.

Q: Where is G418 typically used in research settings?

A: G418 is primarily used in laboratories for cell culture and selection processes, specifically to isolate genetically modified prokaryotic or eukaryotic cells following gene transfer experiments.

Q: What is the process for dissolving G418 before use?

A: To prepare G418, dissolve it in sterile water at a concentration of up to 50mg/mL. Make sure the solution matches the required application pH (4.55.5) and is appropriately filtered for cell culture use.

Q: What benefit does G418 offer for cell culture experiments?

A: G418 provides reliable selection of genetically engineered cells by effectively inhibiting non-resistant cell lines, which enhances the accuracy and outcomes of genetic research and biotechnological studies.

Q: When should custom packing be considered for G418 orders?

A: Custom packing is advisable when specific quantities or packaging formats are needed for larger projects, unique applications, or to match storage requirements in different research facilities.

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