Borrelidin

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Borrelidin

An angiogenesis inhibitor

A macrolide antibiotic isolated from Streptomyces sp. An antiangiogenic (IC = 0.8 nM) agent. Bacterial and eukaryal threonyl-tRNA synthetase (THrRS) inhibitor. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Also acts as a CDK inhibitor

SKU: 2367

Availability: In stock

SKU-Size

2367-250	250 g	15,950
2367-1000	1 mg	46,750

Alternate Name	Treponemycin; U 78548; C2989
Peptide Sequence	White to off-white solid
Formulation	7184-60-3
CAS #	CHNO
Molecular Formula	489.64
Molecular Weight	98% by HPLC
Purity	DMSO (~10 mg/ml)
Solubility	Protect from light and moisture
SMILES	CC1CC(CC(C(C(=CC=CCC(OC(=O)CC(C(C1)C)O)C2CCCC2C(=O)O)C#N)O)C)C
InChi	InChI=1S/C28H43NO6/c1-17-12-18(2)14-20(4)27(32)21(16-29)8-5-6-11-25(22-9-7-10-23(22)28(33)34)35-26(31)15-24(30)19(3)13-17/h5-6,8,17-20,22-25,27,30,32H,7,9-15H2,1-4H3,(H,33,34)/b6-5+,21-8-/t17-,18+,19-,20-,22+,23+,24-,25-,27+/m0/s1
InChi Key	OJCKRNPLOZHAOU-UGKRXNSESA-N
PubChem CID	6436801
MDL Number	MFCD01740784
Storage Conditions	-20 C
Shipping Conditions	Gel Pack
USAGE	For Research Use Only! Not For Use in Humans. Address: D-17, Plot No : 283, second floor, Sector-3, Rohini, Delhi 110085 Contact: +91-9990521622,

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