|Alternate Names||Leukocyte surface antigen CD53,CD53,Cell surface glycoprotein CD53,Tetraspanin-25,Tspan-25,MOX44, TSPAN25|
|Background||CD53 is a 35-42 kD type III tetraspan membrane protein. It is expressed on all leukocytes, but not on platelets or erythrocytes. CD53 is thought to be involved in signal transduction. It has been shown to interact with a number of proteins including IL-4, CD20, CD2, CD9, IL-2, VLA-4, and CD4. Cross-linking of CD53 promotes B cell activation. The CD53 antigen is highly glycosylated and treatment with endoglycosidase F reduces the apparent molecular weight of this protein by approximately 25 kD.|
|Clone No.||C53-2 (See Other Available Formats)|
|Isotype||Mouse IgG2a, ÃÂº|
|Isotype Control||Mouse IgG2a, ÃÂº Isotype Control(AF647 Conjugated)[C1.18.4] [Product E-AB-F09802M]|
|Application||FCM (See the Application Description)|
|Storage Buffer||PBS with 0.05% Proclin300, 1% BSA|
|Shipping||Biological ice pack at 4 Ã¢âÆ|
|Stability & Storage||Keep as concentrated solution. |
Store at 2~8Ã¢âÆ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.