|Alternate Names||GP3A,GPIIIa,ITGB3,Integrin beta-3|
|Background||CD61, also known as integrin Î²3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin Î±V (CD51) to form Î±V/Î²3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.|
|Clone No.||VI-PL2 (See Other Available Formats)|
|Isotype||Mouse IgG1, |
|Isotype Control||Mouse IgG1, Isotype Control(PE Conjugated)[MOPC-21] [Product E-AB-F09792D]|
|Application||FCM (See the Application Description)|
|Storage Buffer||PBS with 0.05% Proclin300, 1% BSA|
|Shipping||Biological ice pack at 4|
|Stability & Storage||Keep as concentrated solution. |
Store at 2~8â„ƒ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.