|Alternate Names||T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain,CD3E/D/G/Z,CD3e/d/g/z,CD3E/D/G/Z,CD3|
|Background||CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ÃÆÅ½ÃâÂµ, ÃÆÅ½ÃâÂ´, ÃÆÅ½ÃâÂ³ and ÃÆÅ½ÃâÂ¶ chains. It forms a TCR complex by associating with TCR ÃÆÅ½ÃâÂ±/ÃÆÅ½ÃâÂ² or ÃÆÅ½ÃâÂ³/ÃÆÅ½ÃâÂ´ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.|
|Clone No.||17A2 (See Other Available Formats)|
|Isotype||Rat IgG2b, ÃÆÅ½ÃâÂº|
|Isotype Control||Rat IgG2b, ÃÆÅ½ÃâÂº Isotype Control(FITC Conjugated)[LTF-2] [Product E-AB-F09842C]|
|Storage Buffer||PBS with 0.05% Proclin300, 1% BSA|
|Shipping||Biological ice pack at 4 ÃÆÂ¢ÃââÃâÆ|
|Stability & Storage||Keep as concentrated solution. |
Store at 2~8ÃÆÂ¢ÃââÃâÆ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 ÃÆÅ½ÃâÂ¼L of antibody per test (million cells in 100 ÃÆâÃâÂµl staining volume or per 100 ÃÆâÃâÂµl of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Mouse splenocytes are stained with Anti-Mouse CD3 Monoclonal Antibody(FITC Conjugated)(filled gray histogram). Unstained splenocytes (blank black histogram) are used as control.