|Home||» Products||» Antibody||» CD3 Monoclonal Antibody|
|Alternate Names||T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain,CD3E/D/G/Z,CD3e/d/g/z,CD3E/D/G/Z,CD3|
|Background||CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ÃƒÂŽÃ‚Âµ, ÃƒÂŽÃ‚Â´, ÃƒÂŽÃ‚Â³ and ÃƒÂŽÃ‚Â¶ chains. It forms a TCR complex by associating with TCR ÃƒÂŽÃ‚Â±/ÃƒÂŽÃ‚Â² or ÃƒÂŽÃ‚Â³/ÃƒÂŽÃ‚Â´ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.|
|Clone No.||17A2 (See Other Available Formats)|
|Isotype||Rat IgG2b, ÃƒÂŽÃ‚Âº|
|Isotype Control||Rat IgG2b, ÃƒÂŽÃ‚Âº Isotype Control(FITC Conjugated)[LTF-2] [Product E-AB-F09842C]|
|Storage Buffer||PBS with 0.05% Proclin300, 1% BSA|
|Shipping||Biological ice pack at 4 ÃƒÂ¢Ã‚Â„Ã‚Âƒ|
|Stability & Storage||Keep as concentrated solution. |
Store at 2~8ÃƒÂ¢Ã‚Â„Ã‚Âƒ and protected from prolonged exposure to light. Do not freeze.Â
Centrifuge before opening to ensure complete recovery of vial contents.Â
This product is guaranteed up to one year from purchase.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 ÃƒÂŽÃ‚Â¼L of antibody per test (million cells in 100 ÃƒÂ‚Ã‚Âµl staining volume or per 100 ÃƒÂ‚Ã‚Âµl of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Mouse splenocytes are stained with Anti-Mouse CD3 Monoclonal Antibody(FITC Conjugated)(filled gray histogram). Unstained splenocytes (blank black histogram) are used as control.