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CD40 Monoclonal Antibody(FITC Conjugated)

CD40 Monoclonal Antibody(FITC Conjugated)
CD40 Monoclonal Antibody(FITC Conjugated)
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Product Code : SRGE05
Brand Name : SR GROUP (ELABSCIENCE BIOTECNOLOGY)
Product Description

Anti-Human CD40 Monoclonal Antibody(FITC Conjugated)[3A8]


Antigen Information

Alternate Names Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5
Uniprot ID P25942
Background CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.

Product Details

Form Liquid
Clone No. 3A8 (See Other Available Formats)
Host Mouse
Isotype Mouse IgG2a, κ
Isotype Control Mouse IgG2a, κ Isotype Control(FITC Conjugated)[C1.18.4] [Product E-AB-F09802C]
Reactivity Human
Application FCM (See the Application Description)
Storage Buffer PBS with 0.05% Proclin300, 1% BSA
Shipping Biological ice pack at 4 ℃
Stability & Storage Keep as concentrated solution.
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.

Fluorophore

Conjugation: FITC

Recommended Use

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µl staining volume or per 100 µl of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Product Data

  • Human peripheral blood lymphocytes are stained with Anti-Human CD40 Monoclonal Antibody(FITC Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.


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