CD86 Monoclonal Antibody(PE/Cyanine7 Conjugated)

Alternate Names

T-lymphocyte activation antigen CD86,Cd86,Activation B7-2 antigen,Early T-cell costimulatory molecule 1,ETC-1

Uniprot ID

P42081

Background

CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Form

Liquid

Clone No.

BU63 (See Other Available Formats)

Host

Mouse

Isotype

Mouse IgG1, º

Isotype Control

Mouse IgG1, º Isotype Control(PE/Cyanine7 Conjugated)[MOPC-21] [Product E-AB-F09792H]

Reactivity

Human

Application

FCM (See the Application Description)

Storage Buffer

PBS with 0.05% Proclin300, 1% BSA

Shipping

Biological ice pack at 4

Stability & Storage

Keep as concentrated solution.
Store at 2~8and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.