JZL 195 Chemical

4800-67200 INR

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Product Details:

Shelf Life 24 Months
Molecular Weight 433.5 Kilograms (kg)
Physical Form Powder
Appearance POWDER
Other Names 4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate
Boiling point REFER C.O.A MSDS
Melting Point REFER C.O.A MSDS
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JZL 195 Chemical Price And Quantity

Price 4800-67200 INR
Minimum Order Quantity 1 Pack

JZL 195 Chemical Product Specifications

Taste Bitter
Melting Point REFER C.O.A MSDS
Shelf Life 24 Months
Physical Form Powder
Color WHITE
Structural Formula C24H23N3O5
Usage R&D FORMULATION
Molecular Weight 433.5 Kilograms (kg)
CAS No 1210004-12-8
Smell Stimulus
Purity(%) 98%
HS Code 3821
Shape Crystal
Ph Level REFER C.O.A MSDS
Chemical Name Other
Molecular Formula C24H23N3O5
Classification High Purity
Type TETRA HYDROXI STEAROL
Other Names 4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate
Boiling point REFER C.O.A MSDS
Appearance POWDER

JZL 195 Chemical Trade Information

Payment Terms Cheque, Days after Acceptance (DA), Cash Advance (CA)
Supply Ability 10 Pack Per Day
Delivery Time 10-15 Days
Sample Available Yes
Sample Policy Within a certain price range free samples are available
Packaging Details 5MG 10MG 50MG 100MG
Main Export Market(s) Asia
Main Domestic Market All India

Product Description

DESCRIPTION

Fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) mediate the hydrolysis of the endocannabinoids arachidonoyl ethanolamide (AEA) and 2-arachidonoylglycerol (2-AG), respectively. JZL 195 is a potent inhibitor of both FAAH and MAGL (IC50s = 2 and 4 nM, respectively).1 It poorly inhibits neuropathy target esterase and ABHD6 and does not inhibit other brain serine hydrolases. JZL 195 displays time-dependent inhibition of FAAH and MAGL in vivo, consistent with a covalent mechanism of activation.1 The in vivo inhibitory actions of JZL 195 against FAAH and MAGL are comparable to those of the selective inhibitors PF-3845 (Item No. 13279) and JZL 184 (Item No. 13158), respectively.1 Through its inhibitory actions, JZL 195 simultaneously augments brain levels of AEA and 2-AG, producing antinociceptive, cataleptic, and hypomotility effects like those produced by direct CB1agonists.1

TECHNICAL INFORMATION

Formal Name

4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate

CAS Number

1210004-12-8

Molecular Formula

C24H23N3O5

Formula Weight

433.5

Purity

98%

Formulation

A crystalline solid

max

273 nm

SHIPPING & STORAGE

Storage

-20C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

2 years

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