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JZL 195 Chemical

JZL 195 Chemical

4800-67200 INR

Product Details:

  • Shape Crystal
  • Smell Stimulus
  • Appearance POWDER
  • Taste Bitter
  • Structural Formula C24H23N3O5
  • Ph Level REFER C.O.A MSDS
  • Usage R&D FORMULATION
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JZL 195 Chemical Price And Quantity

  • 1 Pack
  • 4800-67200 INR

JZL 195 Chemical Product Specifications

  • REFER C.O.A MSDS
  • R&D FORMULATION
  • 24 Months
  • 1210004-12-8
  • 4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate
  • C24H23N3O5
  • Powder
  • Bitter
  • REFER C.O.A MSDS
  • 3821
  • Other
  • TETRA HYDROXI STEAROL
  • High Purity
  • 433.5 Kilograms (kg)
  • C24H23N3O5
  • POWDER
  • WHITE
  • REFER C.O.A MSDS
  • Stimulus
  • 98%
  • Crystal

JZL 195 Chemical Trade Information

  • Cheque Days after Acceptance (DA) Cash Advance (CA)
  • 10 Pack Per Day
  • 10-15 Days
  • Yes
  • Within a certain price range free samples are available
  • 5MG 10MG 50MG 100MG
  • Asia
  • All India

Product Description

DESCRIPTION

Fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) mediate the hydrolysis of the endocannabinoids arachidonoyl ethanolamide (AEA) and 2-arachidonoylglycerol (2-AG), respectively. JZL 195 is a potent inhibitor of both FAAH and MAGL (IC50s = 2 and 4 nM, respectively).1 It poorly inhibits neuropathy target esterase and ABHD6 and does not inhibit other brain serine hydrolases. JZL 195 displays time-dependent inhibition of FAAH and MAGL in vivo, consistent with a covalent mechanism of activation.1 The in vivo inhibitory actions of JZL 195 against FAAH and MAGL are comparable to those of the selective inhibitors PF-3845 (Item No. 13279) and JZL 184 (Item No. 13158), respectively.1 Through its inhibitory actions, JZL 195 simultaneously augments brain levels of AEA and 2-AG, producing antinociceptive, cataleptic, and hypomotility effects like those produced by direct CB1agonists.1

TECHNICAL INFORMATION

Formal Name

4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate

CAS Number

1210004-12-8

Molecular Formula

C24H23N3O5

Formula Weight

433.5

Purity

98%

Formulation

A crystalline solid

max

273 nm

SHIPPING & STORAGE

Storage

 

-20C

Shipping

Room temperature in continental US; may vary elsewhere

Stability

2 years


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